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Oxford Laboratories Awards for Excellence

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Presenting the Oxford Laboratories Awards

Based on publications during the past year, the members of the Society for Comparative Endocrinology have selected the following as the 2016 Oxford Laboratories Awardees for Excellence in the advancement of knowledge concerning small animal endocrinology are being presented in two categories: Basic Science and Clinical Studies:

2016 Award Winners

Basic Science:

First Place:
Awardee: Alisdair M. Boag
Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Scotland, United Kingdom EH25 9RG

Publication: Boag AM, Christie MR, McLaughlin KA, Syme HM, Graham P, and  Catchpole B, Autoantibodies against Cytochrome P450 Side-Chain Cleavage Enzyme in Dogs (Canis lupus familiaris) Affected with Hypoadrenocorticism (Addison’s Disease). PLoS One. 2015; 10(11): e0143458

Second Place:
Awardee: Miriam M.J. Kool
Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The Netherlands

Publication: Kool MM, Galac S, van der Helm N, Spandauw CG, Kooistra HS, Mol JA. Expression of somatostatin, dopamine, progesterone and growth hormone receptor mRNA in canine cortisol-secreting adrenocortical tumours. Vet J. 2015; 206(1):108-10.

Clinical Studies:

First Place:
Awardee: Linda A. Frank
Department of Small Animal Clinical Sciences
College of Veterinary Medicine
The University of Tennessee, C247 Veterinary Medical Center, Knoxville, TN 37996-4544

Publication: Frank LA, Henry GA, Whittemore JC, Enders BD, Mawby DI, Rohrbach BW. Serum Cortisol Concentrations in Dogs with Pituitary-Dependent Hyperadrenocorticism and Atypical Hyperadrenocorticism. JVIM 2015;29:193-199.

Second Place:
Awardee: Susan Gottlieb
University of Queensland, School of Veterinary Science, Brisbane, Queensland, Australia

Publication: Gottlieb S, Rand JS, Marshall R, Morton J. Glycemic Status and Predictors of Relapse for Diabetic Cats in Remission. JVIM 2015;29:184-192.

2015 Award Winners

Basic Science:

Karin Albers-Wolthers, Jeffrey de Gier, Hans S. Kooistra, Victor P.M.G. Rutten, Peter J.S. van Kooten, Janneke J. de Graaf, Peter A.J. Leegwater, Robert P. Millar and Auke C. Schaefers-Okkens. Identification of a Novel Kisspeptin with High Gonadotrophin Stimulatory Activity in the Dog. Neuroendocrinology 99, 178-179 (2015).

Yaiza Forcada, A. Holder, D.B. Church, and B. Catchpole. A Polymorphism in the Melanocortin 4 Receptor Gene (MC4R:c.92C>T) Is Associated with Diabetes Mellitus in Overweight Domestic Shorthaired Cats. Journal Of Veterinary Internal Medicine 28, 458-464 (2014).

Clinical studies:

T.L. Williams, J. Elliott and H.M. Syme. Effect on Renal Function of Restoration of Euthyroidism in Hyperthyroid Cats with Iatrogenic Hypothyroidism Journal Of Veterinary Internal Medicine 28, 1251–1255 (2014).

Lathan P, Scott-Moncrieff JC, Wills RW Use of the Cortisol-to-ACTH Ratio for Diagnosis of Primary Hypoadrenocorticism in Dogs. Journal Of Veterinary Internal Medicine  28, 1546-1550 (2014).

2014 Award Winners

Basic Science:

Margarethe Hoenig, Nicole Pach, Karl Thomaseth, Anh Le, David Schaeffer, and Duncan C. Ferguson. Cats differ from other species in their cytokine and antioxidant enzyme response when developing obesityObesity Biology and Integrated Physiology 2013, V 21, pp E407-E414.

Karl RJ Link, Ilana Allio, Jacqueline S Rand, Elisabeth Eppler. The effect of experimentally induced chronic hyperglycaemia on serum and pancreatic insulin, pancreatic islet IGF-1 and plasma and urinary ketones in the domestic cat (Felis felis). General and Comparative Endocrinology 2013, V 188, pp 269-281.

Clinical studies:

Sylvia Djajadiningrat-Laanen, S Galac, MH Boeve, SAEB Boroffka, EC Naan, J IJzer, and HS Kooistra. Evaluation of the Oral Fludrocortisone Suppression Test for Diagnosing Primary Hyperaldosteronism in CatsJVIM 2013;27:1493-1499.

Ruth Gostelow, N Bridger, and HM Syme. Plasma-Free Metanephrine and Free Normetanephrine Measurement for the Diagnosis of Pheochromocytoma in DogsJVIM 2013;27:83-90.

2013 Award Winners

Basic Science:

Massey J, Boag A, Short A, et al.  MHC class II association study in eight breeds of dog with hypoadrenocorticismImmunogenetics 65:291-97.

Niessen SJM, Fernandez-Fuente M, Mahmoud A, et al. Novel diabetes mellitus treatment: mature canine insulin production by canine striated muscle through gene therapyDomes Anim Endo 2012; 43:16-25.

Clinical studies:

Scott-Moncrieff JC, Moore G, Coe J, et al. Characteristics of commercially manufactured and compounded protamine zinc insulinJAVMA 2012; 240:600-606.

Kook PH, Baloi P, Ruetten M, et al. Feasibility and Safety of Endoscopic Ultrasound-guided Fine Needle Aspiration of the Pancreas in Dogs.  J Vet Int Med 2012; 26:513-17.

2012 Award Winners

Basic Science:

Hoenig, M., Jordan, E.T., Glushka, J., Kley, S., Patil, A., Waldron, M., Prestegard, J.H., Ferguson, D.C., Wu, S., and Olson, D.E.  Effect of macronutrients, age, and obesity on 6- and 24-h postprandial glucose metabolism in cats. Am J Physiol Regul Integr Comp Physiol 301: R1798–R1807, 2011.

Kley, S.; Hoenig, M.; Glushka, J.; Jin, E.S.; Burgess, S.C.; Waldron, M.; Jordan, E.T.; Prestegard, J.H.; Ferguson, D.C.; Wu, S.; Olson, D.E.; The Impact of Obesity, Sex, and Diet on Hepatic Glucose Production in Cats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 296.4 (2009): R936-43.

Clinical studies:

Zini, E.; Osto, M.; Franchini, M.; Guscetti, F.; Donath, M.Y.; Perren, A.; Heller, R.S.; Linscheid, P.; Bouwman, M.; Ackermann, M; Lutz, T.A.; Reusch, C.E.; Hyperglycaemia but Not Hyperlipidaemia Causes Beta Cell Dysfunction and Beta Cell Loss in the Domestic Cat.  Diabetologia 52.2 (2009): 336-46.

Pineiro, M. I. R.; Benchekroun, G.; de Fornel-Thibaud, P.; Maurey-Guenec, C.; Garnier, F.; Rosenberg, D.;  Accuracy of an Adrenocorticotropic Hormone (ACTH) Immunoluminometric Assay for Differentiating ACTH-Dependent from ACTH-Independent Hyperadrenocorticism in Dogs.  Journal of Veterinary Internal Medicine 23.4 (2009): 850-5.

2011 Award Winners

Basic Science:

Galac, S, Kars VJ, Klarenbeek, S, Teerds ,KJ, Mol ,JA, Kooistra, HS. Expression of Receptors for Luteinizing Hormone, Gastric-Inhibitory Polypeptide, and Vasopressin in Normal Adrenal Glands and Cortisol-Secreting Adrenocortical Tumors in Dogs. Domestic animal endocrinology 39, 63-75 .1 (2010).

Rivera, N, Ramnanan, CJ, An, Z, Farmer, T, Smith, M, Farmer, B Irimia, JM,  Snead, W, Lautz, M,  Roach, PJ, Cherrington, AD. Insulin-Induced Hypoglycemia Increases Hepatic Sensitivity to Glucagon in Dogs. The Journal of Clinical Investigation 120, 4425-35 (2010).

Clinical studies:

Quante, S, Boretti, FS, Kook, PH, Mueller, C , Schellenberg, S, Zini, E, Sieber-Ruckstuhl, N, Reusch CE. Urinary Catecholamine and Metanephrine to Creatinine Ratios in Dogs with Hyperadrenocorticism or Pheochromocytoma, and in Healthy Dogs. J Vet Intern Med 24,1093-7 (2010).

Williams, TL, Elliott, J and Syme, HM. Association of Iatrogenic Hypothyroidism with Azotemia and Reduced Survival Time in Cats Treated for Hyperthyroidism. J Vet Intern Med 24, 1086-92 (2010).

2010 Award Winners

Basic Science:

DiazEspineira, M. M.; Mol, J.A.; Rijnberk, A.; Kooistra, H.S.; Adenohypophyseal Function in Dogs with Primary Hypothyroidism and Nonthyroidal Illness. Journal of Veterinary Internal Medicine 23.1 (2009):100-7.

Kley, S.; Hoenig, M.; Glushka, J.; Jin, E.S.; Burgess, S.C.; Waldron, M.; Jordan, E.T.; Prestegard, J.H.; Ferguson, D.C.; Wu, S.; Olson, D.E.; The Impact of Obesity, Sex, and Diet on Hepatic Glucose Production in Cats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 296.4 (2009): R936-43.

Clinical studies:

Zini, E.; Osto, M.; Franchini, M.; Guscetti, F.; Donath, M.Y.; Perren, A.; Heller, R.S.; Linscheid, P.; Bouwman, M.; Ackermann, M; Lutz, T.A.; Reusch, C.E.; Hyperglycaemia but Not Hyperlipidaemia Causes Beta Cell Dysfunction and Beta Cell Loss in the Domestic Cat. Diabetologia 52.2 (2009): 336-46.

Pineiro, M. I. R.; Benchekroun, G.; de Fornel-Thibaud, P.; Maurey-Guenec, C.; Garnier, F.; Rosenberg, D.; Accuracy of an Adrenocorticotropic Hormone (ACTH) Immunoluminometric Assay for Differentiating ACTH-Dependent from ACTH-Independent Hyperadrenocorticism in Dogs. Journal of Veterinary Internal Medicine 23.4 (2009): 850-5.

2009 Award Winners

Basic Science:

DiazEspineira, M. M.; Mol, J.A.; Rijnberk, A.; Kooistra, H.S.; Adenohypophyseal Function in Dogs with Primary Hypothyroidism and Nonthyroidal Illness. Journal of Veterinary Internal Medicine 23.1 (2009):100-7.

Kley, S.; Hoenig, M.; Glushka, J.; Jin, E.S.; Burgess, S.C.; Waldron, M.; Jordan, E.T.; Prestegard, J.H.; Ferguson, D.C.; Wu, S.; Olson, D.E.; The Impact of Obesity, Sex, and Diet on Hepatic Glucose Production in Cats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 296.4 (2009): R936-43.

Clinical studies:

Zini, E.; Osto, M.; Franchini, M.; Guscetti, F.; Donath, M.Y.; Perren, A.; Heller, R.S.; Linscheid, P.; Bouwman, M.; Ackermann, M; Lutz, T.A.; Reusch, C.E.; Hyperglycaemia but Not Hyperlipidaemia Causes Beta Cell Dysfunction and Beta Cell Loss in the Domestic Cat.  Diabetologia 52.2 (2009): 336-46.

Pineiro, M. I. R.; Benchekroun, G.; de Fornel-Thibaud, P.; Maurey-Guenec, C.; Garnier, F.; Rosenberg, D.;  Accuracy of an Adrenocorticotropic Hormone (ACTH) Immunoluminometric Assay for Differentiating ACTH-Dependent from ACTH-Independent Hyperadrenocorticism in Dogs.  Journal of Veterinary Internal Medicine 23.4 (2009): 850-5.